Integrated fluorescence sensing for lab-on-a-chip devices

Integrated Fluorescence Sensing for Lab-on-a-Chip Devices

H. Ji, M. Dandin, P. Abshire, and E. Smela, “Integrated Fluorescence Sensing for Lab-on-a-Chip Devices,” in 2006 IEEE/NLM Life Science Systems and Applications Workshop, 2006, pp. 1–2. [Online Article]
Integrated fluorescence sensing for lab-on-a-chip devices

A low noise optical sensor and biocompatible microscale optical filters for integrated fluorescence sensors were developed and tested. The sensor was fabricated in a 0.5 mum CMOS process. The measured reset noise of the sensor is reduced by a factor of 10 compared to conventional active pixel sensors. The transmission ratio in the pass-band and suppression ratio in the stop-band of the optical filters are comparable to that of macroscopic commercial filters for fluorescence microscopy